Autogolous Bone Marrow Stem Cell Study

January 12th, 2011 | Posted by admin in Research

There is accumulating evidence that shows that the placement of hematopoietic cells in the brain may increase growth-enhancing factors of axons and generate active neurons in the receptor. It has been found that after introducing hematopoietic cells in the subarachnoid space of the spinal cord, these cells may be transported through the cerebrospinal fluid and can be deliver more efficiently to the injured area, when compared to the intravenous route. Patients will be stimulated 5 times and then harvest the bone marrow. Bone marrow will be processed in order to obtain hematopoietic cells (CD34+) and minimize the erythrocytes amount. A inoculum of 8 to 10mL of stem cells will be infused intrathecally. Patients will be evaluated with the “Battelle Developmental Inventory” before the procedure and one and three months after that. – Dr. Mancias-Guerra University Hosiptial Monterrey MX.

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3 Responses

  • Claudy Maes says:

    Does this mean that Autologous stem cells from the bone marrow delivered in the spinal fluid by lumbar puncture be more effective than intravenous delivery?
    I was looking into going to Germany with my 3 year old son for his cp and recently discovered that X-cell Center is no longer using the Lumbar Puncture delivery, and is now using IntraVenous injection of stem cells with mannitol.
    If not as effective, is IV safer than LP?
    Which delivery method will the clinical trials by Dr. Cox and Dr. Caroll be using?
    I would feel a lot more comfortable doing a procedure here in the U.S rather than going abroad,
    but time is ticking. I would go to China, Mexico, anywhere in the world to help my son walk NOW.

  • Ronnie says:

    Hi
    it seems that the clinical trail above has been completed. Does anyone knows what are the results ?? It Sounds very promising

  • Jennifer Vogen says:

    I am in a similar situation with a son who is 5 and has CP. A representative from X-Cell Clinic in Germany told me that they still believe the lumbar puncture is the most effective method to administer the treatment, but the German Government is conducting a review and placing barriers up for them to continue to utilize this method. I am also in search of any way to find this treatment for my son.



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